Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
Abstract
Stress leaves a lasting impression on an organism and reshapes future responses. However, the influence of past experience and stress hormones on the activity of neural stress circuits remains unclear. Hypothalamic corticotropin-releasing hormone (CRH) neurons orchestrate behavioral and endocrine responses to stress and are themselves highly sensitive to corticosteroid (CORT) stress hormones. Here, using in vivo optical recordings, we find that...
Paper Details
Title
Stress experience and hormone feedback tune distinct components of hypothalamic CRH neuron activity
Published Date
Dec 13, 2019
Journal
Volume
10
Issue
1
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