Ten questions to consider when interpreting results of a meta‐epidemiological study—the MetaBLIND study as a case

Randomized clinical trials underpin evidence‐based clinical practice, but flaws in their conduct may lead to biased estimates of intervention effects and hence invalid treatment recommendations. The main approach to the empirical study of bias is to collate a number of meta‐analyses and, within each, compare the results of trials with and without a methodological characteristic such as blinding of participants and health professionals. Estimated...