Protein kinase�C promotes choline transporter‑like protein�1 function via improved cell surface expression in immortalized human hepatic cells

Published: Dec 18, 2019
Abstract
Choline is used to synthesize phospholipids and a lack of choline induces a number of liver‑related diseases, including non‑alcoholic steatohepatitis. The current study characterized the choline uptake system, at molecular and functional levels, in the immortalized human hepatic cell line, Fa2N‑4, to identify the specific choline transporter involved in choline uptake. The present study also assesed whether choline deficiency or the inhibited...
Paper Details
Title
Protein kinase�C promotes choline transporter‑like protein�1 function via improved cell surface expression in immortalized human hepatic cells
Published Date
Dec 18, 2019
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