Reprogramming: identifying the mechanisms that safeguard cell identity
Abstract
Development and homeostasis rely upon concerted regulatory pathways to establish the specialized cell types needed for tissue function. Once a cell type is specified, the processes that restrict and maintain cell fate are equally important in ensuring tissue integrity. Over the past decade, several approaches to experimentally reprogram cell fate have emerged. Importantly, efforts to improve and understand these approaches have uncovered novel...
Paper Details
Title
Reprogramming: identifying the mechanisms that safeguard cell identity
Published Date
Dec 1, 2019
Journal
Volume
146
Issue
23
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Notes
History