Integrative proteomics and phosphoproteomics in pulmonary arterial hypertension
Abstract
Pulmonary arterial endothelial cells (PAEC) are mechanistically linked to origins of pulmonary arterial hypertension (PAH). Here, global proteomics and phosphoproteomics of PAEC from PAH ( n = 4) and healthy lungs ( n = 5) were performed using LC-MS/MS to confirm known pathways and identify new areas of investigation in PAH. Among PAH and control cells, 170 proteins and 240 phosphopeptides were differentially expressed; of these, 45 proteins and...
Paper Details
Title
Integrative proteomics and phosphoproteomics in pulmonary arterial hypertension
Published Date
Dec 9, 2019
Journal
Volume
9
Issue
1
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