Nod2 Protects the Gut From Experimental Colitis Spreading to Small Intestine

Volume: 14, Issue: 5, Pages: 669 - 679
Published: Nov 30, 2019
Abstract
Background and Aims Nucleotide oligomerization domain 2 [NOD2] mutations are key risk factors for Crohn’s disease [CD]. NOD2 contributes to intestinal homeostasis by regulating innate and adaptive immunity together with intestinal epithelial function. However, the exact roles of NOD2 in CD and other NOD2-associated disorders remain poorly known. Methods We initially observed that NOD2 expression was increased in epithelial cells away from...
Paper Details
Title
Nod2 Protects the Gut From Experimental Colitis Spreading to Small Intestine
Published Date
Nov 30, 2019
Volume
14
Issue
5
Pages
669 - 679
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