Umbrella review and meta-analysis of antiplatelet therapy for peripheral artery disease

Background The literature on antiplatelet therapy for peripheral artery disease has historically been summarized inconsistently, leading to conflict between international guidelines. An umbrella review and meta-analysis was performed to summarize the literature, allow assessment of competing safety risks and clinical benefits, and identify weak areas for future research. Methods MEDLINE, Embase, DARE, PROSPERO and Cochrane databases were...