Connexin‐mediated cell communication in the kidney: A potential therapeutic target for future intervention of diabetic kidney disease?
Abstract
The ability of cells to communicate and synchronise their activity is essential for the maintenance of tissue structure, integrity and function. A family of membrane-bound proteins called connexins are largely responsible for mediating the local transfer of information between cells. Assembled in the cell membrane as a hexameric connexon, they function either as a conduit for paracrine signalling, forming a trans-membrane hemi-channel or, if...
Paper Details
Title
Connexin‐mediated cell communication in the kidney: A potential therapeutic target for future intervention of diabetic kidney disease?
Published Date
Jan 15, 2020
Journal
Volume
105
Issue
2
Pages
219 - 229
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History