Connexin‐mediated cell communication in the kidney: A potential therapeutic target for future intervention of diabetic kidney disease?

Volume: 105, Issue: 2, Pages: 219 - 229
Published: Jan 15, 2020
Abstract
The ability of cells to communicate and synchronise their activity is essential for the maintenance of tissue structure, integrity and function. A family of membrane-bound proteins called connexins are largely responsible for mediating the local transfer of information between cells. Assembled in the cell membrane as a hexameric connexon, they function either as a conduit for paracrine signalling, forming a trans-membrane hemi-channel or, if...
Paper Details
Title
Connexin‐mediated cell communication in the kidney: A potential therapeutic target for future intervention of diabetic kidney disease?
Published Date
Jan 15, 2020
Volume
105
Issue
2
Pages
219 - 229
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