Association of plasma-soluble ST2 and galectin-3 with cardiovascular events and mortality following cardiac surgery

Cardiac surgery induces hemodynamic stress on the myocardium, and this process can be associated with significant post-operative morbidity and mortality. Soluble suppression of tumorigenicity 2 (sST2) and galectin-3 (gal-3) are biomarkers of myocardial remodeling and fibrosis; however, their potential association with post-operative changes is unknown. We measured peri-operative plasma sST2 and gal-3 levels in two prospective cohorts (TRIBE-AKI...