Quantification of sheet nacre morphogenesis using X-ray nanotomography and deep learning

High-resolution three-dimensional imaging is key to our understanding of biological tissue formation and function. Recent developments in synchrotron-based X-Ray tomography techniques provide unprecedented morphological information on relatively large sample volumes with a spatial resolution better than 50 nm. However, the analysis of the generated data, in particular image segmentation – separation into structure and background – still presents...