HOXB2 is a Putative Tumour Promotor in Human Bladder Cancer

Background/Aim: The present study aimed to investigate the role of Homebox B2 (HOXB2) in bladder cancer (BC). Materials and Methods: The Cancer Genome Atlas (TCGA) dataset was used to analyse HOXB2 expression in BC. The influence of HOXB2 on the cellular functions of BC cells was determined in both HOXB2 knockdown and HOXB2 overexpressed BC cell lines using in vitro assays. Results: HOXB2 mRNA was significantly upregulated in luminal infiltrated...