High Levels of Lipocalin-2 (NGAL) in Blood of Patients with a Ruptured Abdominal Aortic Aneurysm

Introduction - In the pathophysiology of abdominal aortic aneurysms (AAA) deterioration of the medial aortic wall layer, by smooth muscle cell (SMC) apoptosis and extracellular matrix (ECM) degeneration, plays a critical role. Reactive oxygen species (ROS) and matrix metalloproteinase-9 (MMP-9) have been recognized as important factors in this mechanism.1,2 In turn, Lipocalin-2, also Neutrophil Gelatinase-Associated Lipocalin (NGAL), is an acute...