Leukocyte telomere length in patients with myotonic dystrophy type I: a pilot study
Volume: 7, Issue: 1, Pages: 126 - 131
Published: Dec 5, 2019
Abstract
Myotonic dystrophy type I (DM1) is an autosomal dominant disease of which clinical manifestations resemble premature aging. We evaluated the contribution of telomere length in pathogenesis in 361 DM1 patients (12 with serial measurements) and 223 unaffected relative controls using qPCR assay. While no differences in baseline leukocyte relative telomere length (RTL) was noted, the data suggested an accelerated RTL attrition in DM1 (discovery...
Paper Details
Title
Leukocyte telomere length in patients with myotonic dystrophy type I: a pilot study
Published Date
Dec 5, 2019
Volume
7
Issue
1
Pages
126 - 131
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