Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis
Volume: 2, Issue: 1, Pages: 100060 - 100060
Published: Feb 1, 2020
Abstract
•A peripheral blood DNA methylation (DNAm) score identifies age acceleration in PSC patients vs. healthy controls.•PSC patients with high age acceleration had significantly more PSC-related events than those with low age acceleration.•These findings may enable stratification of at-risk PSC patients based on a DNAm score from peripheral blood. Background & AimsA DNA methylation (DNAm) signature derived from 353 CpG sites (the Horvath clock) has...
Paper Details
Title
Methylation signatures in peripheral blood are associated with marked age acceleration and disease progression in patients with primary sclerosing cholangitis
Published Date
Feb 1, 2020
Volume
2
Issue
1
Pages
100060 - 100060
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History