Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study
Abstract
Background Lifestyle interventions to reduce body mass index (BMI) are critical public health strategies for type 2 diabetes prevention. While weight loss interventions have shown demonstrable benefit for high-risk and prediabetic individuals, we aimed to determine whether the same benefits apply to those at lower risk. Methods and findings We performed a multi-stratum Mendelian randomization study of the effect size of BMI on diabetes odds in...
Paper Details
Title
Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study
Published Date
Dec 10, 2019
Journal
Volume
16
Issue
12
Pages
e1002982 - e1002982
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