Molecular characterization of functional UDP-glucuronosyltransferases 1A and 2B in common marmosets
Abstract
UDP-glucuronosyltransferases (UGTs) are essential drug-conjugation enzymes that metabolize a variety of endobiotic and xenobiotic substrates. The molecular characteristics of UGTs have been extensively investigated in humans, but remain to be investigated in common marmosets, a nonhuman primate species widely used in drug metabolism studies. In this study, 11 UGT cDNAs (UGT1A1, 1A3, 1A4, 1A6, 1A7, and 1A9; and UGT2B49, 2B50, 2B51, 2B52, and...
Paper Details
Title
Molecular characterization of functional UDP-glucuronosyltransferases 1A and 2B in common marmosets
Published Date
Feb 1, 2020
Journal
Volume
172
Pages
113748 - 113748
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