Proton Pump Inhibitors and Kidney Function Decline in Community-Dwelling Older Adults

We thank Drs Soysal and colleagues for their important comment that proton pump inhibitors (PPIs), often given in combination with nonsteroidal anti-inflammatory drugs (NSAIDs), may have added to the decrease in kidney function observed with NSAID use. We therefore performed additional analyses in our data set to explore this important concern. Comment on “Polypharmacy and Kidney Function in Community-Dwelling Adults Age 60 Years and Older: A...