Review paper
Adaptive trial designs in diagnostic accuracy research
Abstract
The aim of diagnostic accuracy studies is to evaluate how accurately a diagnostic test can distinguish diseased from nondiseased individuals. Depending on the research question, different study designs and accuracy measures are appropriate. As the prior knowledge in the planning phase is often very limited, modifications of design aspects such as the sample size during the ongoing trial could increase the efficiency of diagnostic trials. In...
Paper Details
Title
Adaptive trial designs in diagnostic accuracy research
Published Date
Nov 27, 2019
Journal
Volume
39
Issue
5
Pages
591 - 601
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