Site-directed RNA editing (SDRE): Off-target effects and their countermeasures
Abstract
Site-directed RNA editing (SDRE) is invaluable to basic research and clinical applications and has emerged as a new frontier in genome editing. The past few years have witnessed a surge of interest in SDRE, with SDRE tools emerging at a breathtaking pace. However, off-target effects of SDRE remain a tough problem, which constitutes a major hurdle to their clinical applications. Here we discuss the diverse strategies for combating off-target...
Paper Details
Title
Site-directed RNA editing (SDRE): Off-target effects and their countermeasures
Published Date
Nov 1, 2019
Volume
46
Issue
11
Pages
531 - 535
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