Multiobjective optimization of gene circuits for metabolic engineering

Volume: 52, Issue: 26, Pages: 13 - 16
Published: Dec 26, 2019
Abstract
null null Metabolic engineering has enabled the production of a wealth of chemicals with microorganisms. Classic strategies for pathway engineering rely on the expression of heterologous enzymes in a host that convert native intermediates into target products. Although traditional implementations are based on open-loop control, recent advances in gene circuit engineering offer opportunities for building feedback systems that dynamically control...
Paper Details
Title
Multiobjective optimization of gene circuits for metabolic engineering
Published Date
Dec 26, 2019
Volume
52
Issue
26
Pages
13 - 16
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