Multi-targeted Screening of Phytoestrogens in Food, Raw Material, and Dietary Supplements by Liquid Chromatography with Tandem Mass Spectrometry

This work was carried out to develop a high-performance liquid chromatography tandem mass spectrometry method for simultaneous determination of 11 marker compounds in phytoestrogen-rich food and dietary supplements (raw materials and formulated products) prepared from various sources: soy, red clover, chastetree, hop, and flax. The method was fully validated and showed detection limits varying from 0.2 to 1.5 μg/mL, average recoveries ranging...