Original paper

Development of classification models for identification of important structural features of isoform-selective histone deacetylase inhibitors (class I)

Volume: 24, Issue: 4, Pages: 1077 - 1094
Published: Nov 26, 2019
Abstract
As one of the hot topics in the epigenetic studies, histone deacetylases inhibitors (HDACIs) have been introduced to treat a variety of diseases such as cancer, immune disorder and neuronal diseases. Given the high numbers of available pathways in which HDACs are involved, the HDACIs that act particularly on Class I or Class II enzymes are considered as possible candidates for anticancer drugs. Due to their effective roles in the onset of cancer...
Paper Details
Title
Development of classification models for identification of important structural features of isoform-selective histone deacetylase inhibitors (class I)
Published Date
Nov 26, 2019
Volume
24
Issue
4
Pages
1077 - 1094
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