Depicting the Landscape of Adipose Tissue-Specific Macrophages and Their Immunometabolic Signatures during Obesity

Obesity is a widespread health condition, which can lead to the development of metabolic disorders, such as type 2 diabetes mellitus, nonalcoholic fatty liver disease and cardiovascular diseases. Obesity is marked by the excessive deposition of fat in adipose tissue sites combined with chronic low-grade inflammation. Within this clinical setting, it is well established that adipose tissue macrophages exhibit prominent roles in regulating...