Total Synthesis of the Proposed Structure of Paraphaeosphaeride C

Volume: 24, Issue: 23, Pages: 4230 - 4230
Published: Nov 21, 2019
Abstract
Paraphaeosphaeride C is a demethoxy derivative of phaeosphaeride A and exhibits STAT3 inhibitory activity. Our previous papers reported the total synthesis of phaeosphaeride A using a diastereoselective vinyl anion aldol reaction as the key step to construct the dihydropyran ring. In this work, the first total synthesis of the proposed structure of paraphaeosphaeride C was achieved via a similar synthetic strategy. The synthetic compound was...
Paper Details
Title
Total Synthesis of the Proposed Structure of Paraphaeosphaeride C
Published Date
Nov 21, 2019
Journal
Volume
24
Issue
23
Pages
4230 - 4230
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