Repeatability and Sensitivity to change of right ventricular analysis methods using cardiac magnetic resonance imaging in PAH: results from the RESPIRE Study

Introduction: Cardiac magnetic resonance imaging (cMRI) metrics are proposed end-points for pulmonary arterial hypertension (PAH) trials. However, the sensitivity to change relative to measurement repeatability is not known. The aim was to determine the repeatability and sensitivity to change of cMRI metrics in PAH. Methods: Patients with PAH had baseline cMRI and at around 6 months, two follow-up cMRI’s within 24 hours. Short axis...