Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
Abstract
Type I CRISPR-Cas systems are abundant and widespread adaptive immune systems in bacteria and can greatly enhance bacterial survival in the face of phage infection. Upon phage infection, some CRISPR-Cas immune responses result in bacterial dormancy or slowed growth, which suggests the outcomes for infected cells may vary between systems. Here we demonstrate that type I CRISPR immunity of Pectobacterium atrosepticum leads to suppression of two...
Paper Details
Title
Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity
Published Date
Dec 4, 2019
Journal
Volume
10
Issue
1
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