Methylglyoxal Metabolism and Aging-Related Disease: Moving from Correlation toward Causation
Volume: 31, Issue: 2, Pages: 81 - 92
Published: Feb 1, 2020
Abstract
Methylglyoxal (MG) is a side-product of mainly glycolysis that together with reactive oxygen species (ROS) leads to cellular dysregulation in age-related diseases and is a potential causal factor behind diabetes. The glyoxalase system is the most important system in the metabolism of MG, but evidence indicates that other enzymes also play an important role in regulating MG levels. Although involved in cellular dysregulation, mild MG stress also...
Paper Details
Title
Methylglyoxal Metabolism and Aging-Related Disease: Moving from Correlation toward Causation
Published Date
Feb 1, 2020
Volume
31
Issue
2
Pages
81 - 92
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