Placental Dna Methylation Is Associated With Birth Weight And Maternal Smoking: An Epigenome-Wide Association Study

Introduction Epigenetics has been suggested to be involved in the association between early-life environment, birth developmental indicators and future health. We examined the association of placental methylation in 426 049 CpGs with birth weight (BW) and maternal pregnancy smoking. Methods Among 668 pregnant women from the well-characterized EDEN mother child cohort, placenta samples were collected at delivery using a standardized protocol. DNA...