Atomic Force Microscopy: The Characterisation of Amyloid Protein Structure in Pathology

Proteins are versatile macromolecules that perform a variety of functions and participate in virtually all cellular processes. The functionality of a protein greatly depends on its structure and alterations may result in the development of diseases. Most well-known of these are protein misfolding disorders, which include Alzheimer's and Parkinson's diseases as well as type 2 diabetes mellitus, where soluble proteins transition into insoluble...