Collagen scaffold-mediated delivery of NLC/siRNA as wound healing materials

Achieving prolonged and localized delivery of small interfering RNA (siRNA) at a specific site is highly desirable, since siRNA therapy has become a promising strategy for many medical applications. Many different synthetic or natural biomaterials have been studied for local sustained drug delivery. Of those, collagen has received increased attention, especially for wound applications, due to its biocompatibility, safety, and hemostatic...