Extracellular ATP as a biomarker of severity of chronic obstructive pulmonary disease

Introduction: Cigarette smoking is the main etiologic factor for chronic obstructive pulmonary disease (COPD), characterized by chronic airway inflammation. Extracellular ATP (eATP) is a damage-associated molecular pattern (DAMP) molecule that may induce activation of inflammatory cells. Aims and Objectives: The aim of this study was to assess eATP concentration in stable COPD patients in relation to the severity of the disease and...