Rare copy number variants in individuals at clinical high risk for psychosis: Enrichment of synaptic/brain‐related functional pathways

Volume: 183, Issue: 2, Pages: 140 - 151
Published: Nov 19, 2019
Abstract
Schizophrenia is a complex and chronic neuropsychiatric disorder, with a heritability of around 60–80%. Large (>100 kb) rare (<1%) copy number variants (CNVs) occur more frequently in schizophrenia patients compared to controls. Currently, there are no studies reporting genome‐wide CNVs in clinical high risk for psychosis (CHR‐P) individuals. The aim of this study was to investigate the role of rare genome‐wide CNVs in 84 CHR‐P individuals...
Paper Details
Title
Rare copy number variants in individuals at clinical high risk for psychosis: Enrichment of synaptic/brain‐related functional pathways
Published Date
Nov 19, 2019
Volume
183
Issue
2
Pages
140 - 151
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