BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design
Abstract
The Bacillus Calmette-Guérin (BCG) is a live attenuated tuberculosis vaccine that has the ability to induce non-specific cross-protection against pathogens that might be unrelated to the target disease. Vaccination with BCG reduces mortality in newborns and induces an improved innate immune response against microorganisms other than Mycobacterium tuberculosis, such as Candida albicans and Staphylococcus aureus. Innate immune cells, including...
Paper Details
Title
BCG-Induced Cross-Protection and Development of Trained Immunity: Implication for Vaccine Design
Published Date
Nov 29, 2019
Journal
Volume
10
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