Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression
Abstract
Structural variants including copy number variations (CNV) have gained widespread attention, especially in pharmacogenomics but for several genes functional relevance and clinical evidence are still lacking. Detection of CNVs in next-generation sequencing data is challenging but offers widespread applications. We developed a cohort-based CNV detection workflow to extract CNVs from read counts of targeted NGS of 340 genes involved in absorption,...
Paper Details
Title
Copy number variation profiling in pharmacogenes using panel-based exome resequencing and correlation to human liver expression
Published Date
Nov 30, 2019
Journal
Volume
139
Issue
2
Pages
137 - 149
Citation AnalysisPro
You’ll need to upgrade your plan to Pro
Looking to understand the true influence of a researcher’s work across journals & affiliations?
- Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
- Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.
Notes
History