Associations of gut microbiota and Chronic Obstructive Pulmonary Disease Assessment Test (CAT) score in chemotherapy treated lung cancer patients with COPD

Introduction: Patients with lung cancer have a high prevalence of chronic obstructive pulmonary disease (COPD). There is a lack in our understanding of pathogenesis and mechanisms accounting for large variability in COPD phenotype. Airway dysbiosis have been implicated with disease severity and exacerbations in COPD. However, the role of gastrointestinal (GI) microbiome in pathogenesis of COPD has not been explored. Recent data suggest...