Periprosthetic Osteolysis: Mechanisms, Prevention and Treatment.
Abstract
Clinical studies, as well as in vitro and in vivo experiments have demonstrated that byproducts from joint replacements induce an inflammatory reaction that can result in periprosthetic osteolysis (PPOL) and aseptic loosening (AL). Particle-stimulated macrophages and other cells release cytokines, chemokines, and other pro-inflammatory substances that perpetuate chronic inflammation, induce osteoclastic bone resorption and suppress bone...
Paper Details
Title
Periprosthetic Osteolysis: Mechanisms, Prevention and Treatment.
Published Date
Dec 1, 2019
Journal
Volume
8
Issue
12
Pages
2091
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Notes
History