Empagliflozin attenuates ischemia and reperfusion injury through LKB1/AMPK signaling pathway

Volume: 501, Pages: 110642 - 110642
Published: Feb 1, 2020
Abstract
The beneficial effects of empagliflozin (EMPA) on cardiac functions during ischemia and reperfusion were characterized. The contractile functions of isolated cardiomyocytes from adult C57BL/6J mice were determined with IonOptix SoftEdgeMyoCam system. The mitochondrial superoxide production was measured by MitoSOX fluorescent probe. The ex vivo isolated heart perfusion system was used to determine the pharmacological effects of EMPA on heart's...
Paper Details
Title
Empagliflozin attenuates ischemia and reperfusion injury through LKB1/AMPK signaling pathway
Published Date
Feb 1, 2020
Volume
501
Pages
110642 - 110642
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