The molecular interplay between progenitors and immune cells in tissue regeneration and homeostasis

Some vertebrates in the animal kingdom including salamanders and teleost fish have the astonishing ability to fully regenerate many appendages and organs throughout their lifespan. In contrast, most mammals exhibit limited regenerative capabilities that decline with age. Over the last decade, cells in both the innate and adaptive immune system have emerged as key players that direct successful appendage and organ regenerative outcomes....