Comparison of polysaccharides in articular cartilage regeneration associated with chondrogenic and autophagy-related gene expression

Articular cartilage exhibits reduced self-healing following degeneration. This research evaluated the effects of hydrogels derived from various polysaccharides—gellan gum (GG), alginate, and agarose—on cartilage regeneration compared with that of hyaluronic acid (HA), which is commonly used in cartilage tissue engineering. Chondrocytes were isolated from the articular cartilage of New Zealand White (NZW) rabbits and stimulated with IL-1β...