A Novel Method for Flow Cytometric Quantification of Human Platelet Membrane Glycoproteins in Citrated Whole Blood

Introduction: Diagnosis of platelet receptor defects can be confirmed by flow cytometry using a panel of monoclonal antibodies. The conventional method utilizing platelet rich plasma (PRP) has many limitations such as time-consuming preparation, requirement of a large sample volume or limitations in samples from patients with thrombocytopenia or abnormally large platelets. In order to overcome these difficulties a novel method was developed...