NEUROPROTECTIVE EFFECT OF APOE2: EVIDENCE AND IMPLICATION FOR COGNITIVE AGING

Apolipoprotein E is a glycoprotein mediator and regulator of lipid transport and uptake. The APOE4 allele has been associated with higher risk of Alzheimer’s disease and of mortality, but the protective effect of the less prevalent APOE2 allele is less well established. This symposium will bring together experts in epidemiology, molecular biology, neurology and systems biology to clarify the role of APOE2 in longevity and cognitive health, to...