Glycosylationof Immunoglobulins Determine Bone Loss in Multiple Myeloma
Abstract
About 80% of patients with multiple myeloma develop a severe osteolytic bone disease causing pain and fractures. The myeloma cells secrete immunoglobulins and the presence of monoclonal immunoglobulins in serum is a hallmark of the disease. Immunoglobulins play a role in bone loss, but have not been linked with the bone disease in multiple myeloma. In this work, we isolated immunoglobulins from serum of myeloma patients using protein G coupled...
Paper Details
Title
Glycosylationof Immunoglobulins Determine Bone Loss in Multiple Myeloma
Published Date
Nov 13, 2019
Journal
Volume
134
Issue
Supplement_1
Pages
4324 - 4324
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