dGEMRIC and CECT Comparison of Cationic and Anionic Contrast Agents in Cadaveric Human Metacarpal Cartilage

Magnetic resonance imaging (MRI) and computed tomography (CT) are widely used to image cartilage and their diagnostic capability is enhanced in the presence of contrast agents. The aim of the study is to directly compare the performance between commercial anionic MRI (Gd(DTPA), Gd2−) and CT (Ioxaglate, Iox1−) contrast agents with novel cationic MRI (Gd(DTPA)Lys 2 , Gd4+) and CT (CA4+) contrast agents for assessment of cartilage mechanical and...