NRG3 contributes to cognitive deficits in chronic patients with schizophrenia

Cognitive deficit is a fundamental trait of schizophrenia, but its mecwhanisms remain unknown. The neuregulin 3 (NRG3) gene, involving in neuronal function, has been considered to be associated with schizophrenia and cognition. However, no study has investigated the effects of NRG3 polymorphism on cognitive deficits in a large sample of the patients with schizophrenia. A total of 1112 schizophrenia patients and 423 controls were recruited and...