Ethanolic extract of Iris songarica rhizome attenuates methotrexate-induced liver and kidney damages in rats.
Abstract
The long-term sequelae of methotrexate (MTX) remain the major cause of concern for both patients and therapists. Therefore, new approaches to decrease MTX side effects are needed. The study was carried out to evaluate the effects of Iris songarica Schrenk (IS) rhizome extract against MTX-induced hepatic and renal injuries in rats.Forty male Wistar rats were randomly divided into five groups (n=8) including control, MTX, IS50, IS150 and IS300....
Paper Details
Title
Ethanolic extract of Iris songarica rhizome attenuates methotrexate-induced liver and kidney damages in rats.
Published Date
Aug 28, 2020
Journal
Volume
10
Issue
4
Pages
372 - 383
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