Pre‐clinical evidence of safety and protective effect of isatin and oxime derivatives against malathion‐induced toxicity

Volume: 126, Issue: 4, Pages: 399 - 410
Published: Dec 2, 2019
Abstract
The inhibition of acetylcholinesterase (AChE) is a common outcome caused by organophosphorus (OPs) intoxication. Although inconsistent, the standard treatment consists of a muscarinic receptor antagonist (atropine) and AChE-reactivating molecules such as oximes. This study proposes to test unpublished compounds which contain the moieties of isatin and/or oxime have protective effects against the toxicity induced by malathion in two animal...
Paper Details
Title
Pre‐clinical evidence of safety and protective effect of isatin and oxime derivatives against malathion‐induced toxicity
Published Date
Dec 2, 2019
Volume
126
Issue
4
Pages
399 - 410
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