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doi.org/10.1155/2019/3124745

The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity

..., Limin Chen
31
Mediators of Inflammation4.60
Volume: 2019, Pages: 1 - 12
Published: Nov 18, 2019
Abstract
Ubiquitin-specific protease 18 (USP18) is involved in immunoregulation and response to interferon- (IFN-) based treatment in patients chronically infected with hepatitis C virus (HCV). We investigated whether and how its upregulation alters HCV infection.Overexpression of wild-type (USP18 WT) or catalytically inactive mutant (USP18 C64S) USP18 was examined for effects on HCV replication in the absence and presence of IFNα or IFNλ using both the...
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Paper Details
Title
The Ubiquitin-Specific Protease 18 Promotes Hepatitis C Virus Production by Increasing Viral Infectivity
DOI
doi.org/10.1155/2019/3124745
Published Date
Nov 18, 2019
Journal
Mediators of Inflammation
Volume
2019
Pages
1 - 12
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