Glutaminolysis and Glycolysis Are Essential for Optimal Replication of Marek’s Disease Virus
Abstract
Viruses may hijack glycolysis, glutaminolysis, or fatty acid β-oxidation of host cells to provide the energy and macromolecules required for efficient viral replication. Marek's disease virus (MDV) causes a deadly lymphoproliferative disease in chickens and modulates metabolism of host cells. Metabolic analysis of MDV-infected chicken embryonic fibroblasts (CEFs) identified elevated levels of metabolites involved in glutamine catabolism, such as...
Paper Details
Title
Glutaminolysis and Glycolysis Are Essential for Optimal Replication of Marek’s Disease Virus
Published Date
Jan 31, 2020
Journal
Volume
94
Issue
4
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