Functional role of respiratory supercomplexes in mice: segmentation of the Qpool and SCAF1

Published: Nov 2, 2019
Abstract
Summary Mitochondrial respiratory complexes assemble into different forms of supercomplexes (SC). In particular, SC III 2 +IV require the SCAF1 protein. However, the structural role of this factor in the formation of the respirasome (I+III 2 +IV) and the physiological role of SCs are controversial. Here, we study C57BL/6J mice harbouring either non-functional SCAF1, the full knock-out for SCAF1 or the wild-type version of the protein and found a...
Paper Details
Title
Functional role of respiratory supercomplexes in mice: segmentation of the Qpool and SCAF1
Published Date
Nov 2, 2019
Journal
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