Comparison of Phenotypes and Risk Factors for Esophageal Adenocarcinoma at Present vs Prior Decades

Background & AimsThe incidence of esophageal adenocarcinoma (EAC) has increased over the past decades. It is unclear if this increase is the result of a new cancer phenotype or an increase in risk factors for EAC. We aimed to compare risk factors, the proportions of intestinal and nonintestinal phenotypes of EAC, and survival times of patients during the 2009 to 2012 time period vs the 1996 to 1997 time period.MethodsWe performed a retrospective...